Christoph Thiemermann Selected Research

Lipopolysaccharides

1/2020	The Effect of β2-Adrenoceptor Agonists on Leucocyte-Endothelial Adhesion in a Rodent Model of Laparotomy and Endotoxemia.
2/2015	Quantification of microcirculatory blood flow: a sensitive and clinically relevant prognostic marker in murine models of sepsis.
1/2015	'Preconditioning' with low dose lipopolysaccharide aggravates the organ injury / dysfunction caused by hemorrhagic shock in rats.
7/2013	Inhibition of IκB kinase reduces the multiple organ dysfunction caused by sepsis in the mouse.
7/2013	Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor.
2/2008	Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat.
3/2007	Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo.
1/2007	Lipoproteins in inflammation and sepsis. I. Basic science.
4/2006	Peroxisome proliferator-activated receptor-gamma antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia.
3/2006	Peptidoglycan--an endotoxin in its own right?

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Christoph Thiemermann Research Topics

Disease

67	Inflammation (Inflammations) 01/2023 - 03/2000
52	Ischemia 03/2024 - 03/2002
48	Shock 03/2024 - 01/2002
48	Sepsis (Septicemia) 01/2023 - 11/2003
47	Reperfusion Injury 01/2024 - 01/2002
23	Endotoxemia 01/2020 - 03/2000
21	Wounds and Injuries (Trauma) 10/2023 - 08/2003
21	Multiple Organ Failure (MODS) 07/2023 - 01/2002
20	Hemorrhagic Shock 05/2024 - 09/2002
20	Necrosis 08/2010 - 01/2002
16	Septic Shock (Toxic Shock Syndrome) 01/2023 - 07/2002
12	Acute Kidney Injury (Acute Renal Failure) 01/2023 - 07/2002
12	Infarction (Infarctions) 10/2013 - 07/2002
11	Hemorrhage 07/2023 - 05/2002
11	Myocardial Infarction 01/2018 - 07/2002
10	Hypotension (Low Blood Pressure) 01/2023 - 04/2003
9	Infections 01/2023 - 09/2002
9	Critical Illness (Critically Ill) 01/2023 - 05/2006
9	Body Weight (Weight, Body) 09/2020 - 10/2002
9	Myocardial Ischemia (Ischemic Heart Diseases) 01/2018 - 07/2002
9	Hypoxia (Hypoxemia) 03/2013 - 08/2003
8	Lung Injury 03/2024 - 01/2002
8	Colitis 03/2024 - 02/2003
7	Obesity 01/2022 - 01/2013
6	Arthritis (Polyarthritis) 01/2024 - 10/2002
6	Pleurisy (Pleuritis) 01/2015 - 01/2002
6	Edema (Dropsy) 08/2008 - 05/2002
5	Insulin Resistance 01/2021 - 08/2010
5	Pneumonia (Pneumonitis) 01/2018 - 12/2010
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2013 - 02/2003
5	Experimental Arthritis 07/2006 - 01/2002
4	Cardiomyopathies (Cardiomyopathy) 01/2022 - 11/2016
4	Type 2 Diabetes Mellitus (MODY) 01/2022 - 03/2005

Drug/Important Bio-Agent (IBA)

26	LigandsIBA 05/2024 - 07/2002
23	CytokinesIBA 01/2022 - 03/2000
21	PPAR gammaIBA 08/2010 - 05/2002
19	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 03/2024 - 03/2000
19	Erythropoietin FDA Link 09/2013 - 07/2004
18	CreatinineIBA 09/2020 - 12/2002
16	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 05/2024 - 07/2002
16	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022 - 03/2000
16	EnzymesIBA 01/2022 - 01/2002
16	LipopolysaccharidesIBA 01/2020 - 04/2003
14	Glycogen Synthase (Synthase I)IBA 01/2024 - 03/2006
14	NF-kappa B (NF-kB)IBA 01/2023 - 01/2002
14	Peroxidase (Myeloperoxidase)IBA 01/2022 - 02/2003
14	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2007 - 12/2002
13	Alanine Transaminase (SGPT)IBA 01/2018 - 03/2004
11	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2023 - 01/2002
11	EndotoxinsIBA 01/2022 - 01/2002
10	Proteins (Proteins, Gene)FDA Link 01/2023 - 07/2002
10	InflammasomesIBA 01/2023 - 01/2013
10	Insulin (Novolin)FDA Link 01/2021 - 03/2005
9	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 03/2024 - 01/2002
9	Urea (Carbamide)FDA LinkGeneric 01/2023 - 12/2002
9	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2022 - 01/2002
9	Peptidoglycan (Murein)IBA 01/2020 - 07/2002
8	5-aminoisoquinolinoneIBA 03/2024 - 01/2002
8	(4- (((2- (3- fluoro- 4- (trifluoromethyl)phenyl)- 4- methyl- 1,3- thiazol- 5- yl)methyl)sulfanyl)- 2- methylphenoxy)acetic acidIBA 01/2018 - 02/2010
8	Transcription Factors (Transcription Factor)IBA 07/2017 - 01/2002
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2013 - 03/2000
8	DNA (Deoxyribonucleic Acid)IBA 03/2013 - 01/2002
8	PPAR-gamma AgonistsIBA 08/2010 - 08/2003
8	3-nitrotyrosineIBA 05/2010 - 05/2002
8	ZymosanIBA 02/2010 - 01/2002
8	4- benzyl- 2- methyl- 1,2,4- thiadiazolidine- 3,5- dioneIBA 01/2009 - 03/2006
7	Phosphotransferases (Kinase)IBA 01/2021 - 03/2012
7	Glycogen Synthase Kinase 3 betaIBA 09/2008 - 09/2005
7	Lipase (Acid Lipase)FDA Link 10/2005 - 05/2002
7	Rosiglitazone (Avandia)FDA Link 03/2005 - 07/2002
6	HDL LipoproteinsIBA 03/2024 - 07/2003
6	BilirubinIBA 01/2023 - 03/2004
6	salicylhydroxamic acid (SHAM)IBA 01/2020 - 02/2007
6	Caspase 3 (Caspase-3)IBA 12/2018 - 08/2003
6	CarrageenanIBA 01/2015 - 01/2002
6	Superoxide DismutaseIBA 09/2008 - 01/2002
6	Interleukin-1beta (Interleukin 1 beta)IBA 02/2008 - 03/2000
6	Malondialdehyde (Propanedial)IBA 03/2005 - 11/2002
5	9-deoxy-delta-9-prostaglandin D2IBA 05/2024 - 07/2002
5	Collagen Type II (Type II Collagen)IBA 01/2024 - 10/2002
5	Agammaglobulinaemia Tyrosine KinaseIBA 01/2023 - 01/2019
5	LipidsIBA 03/2021 - 01/2007
5	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 12/2013 - 05/2003
5	Glycogen Synthase KinasesIBA 05/2012 - 01/2007
5	PPAR alphaIBA 08/2010 - 07/2002
5	Interleukin-6 (Interleukin 6)IBA 08/2010 - 06/2002
5	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 02/2010 - 10/2005
5	SodiumIBA 03/2009 - 07/2002
5	Poly(ADP-ribose) Polymerase InhibitorsIBA 12/2008 - 01/2002
5	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 09/2008 - 05/2005
5	Creatine Kinase (Creatine Phosphokinase)IBA 01/2007 - 03/2004
5	DinitrobenzenesIBA 01/2005 - 02/2003
4	acalabrutinibIBA 01/2023 - 01/2019
4	ibrutinibIBA 01/2023 - 01/2019
4	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 06/2007

Therapy/Procedure

37	Therapeutics 10/2023 - 01/2002
22	Resuscitation 03/2024 - 09/2002
17	Ligation 01/2023 - 08/2003
16	Punctures 01/2023 - 02/2006
7	Critical Care (Surgical Intensive Care) 10/2018 - 09/2004